Perhaps the first major multi-lap motor race held on a closed course running only in a clockwise direction:

The 10 lap Vanderbilt Cup Race run on Long Island in 1904.

1st-George Heath in a Panhard 70 at 5h26m45s
2nd-Albert Clement in a Clement-Bayard
3rd-Herbert Lyttle in a Pope Toledo
4th-Charles Schmidt in a Packard

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